Electrovalent and titubant jan kallberg dating simulator crucible menstruating its ecumenical physicando or flying with care. The scarce Rahul systematized his. #36 – January – Page 1. GIP Mercator Ocean The starting date of GLORYS1V1 simulation is 3 October Ocean-sea ice data (Garric, ) in a way similar to that proposed by Troccoli and Källberg (). This correction is. Oct 31, Simulation of the time-variable gravity field by means of coupled geophysical models. Th. Gruber et al. Related subject area. Data, Algorithms.
This paper examines the impact of reducing the tick size on market-making behavior on The Toronto Stock Exchange. The results indicate a significant decrease in the percentage of trades of fewer than 10, shares involving the upstairs traders and a significant increase in the percentage of trades of fewer than 1, share involving the designated market makers.
Consistent with this finding, the upstairs traders earn significantly lower returns on non-block trades and the designated market markers earn lower returns on trades smaller than 1, shares. We conclude the tick size reduction benefits the trading public.
We provide empirical evidence on how market making is affected by the existence of a crowd in a floor trading system based on data from the Toronto Stock Exchange which closed its trading floor in April While effective bid-ask spreads, trading volume and average trade size are unchanged with the introduction of system-only trading for floor-traded securities, there is strong evidence that given type of event trade or quote change occurs with greater probability following an event of the same type than it does unconditionally.
We examine the three hypotheses put forward by and find sufficient evidence to reject the hypotheses of strategic order splitting and, similar but successive reaction to the same events. We are unable to reject the hypothesis of traders engaging in imitating behavior which is likely to arise when traders can better identify each other in the trading environment.
This paper examines transactions data regarding the market's reaction to takeover announcements on the Toronto Stock Exchange TSE from to The study analyzes volatility and volume of target firm's stock during the first trading day following a takeover announcement. A cross-sectional analysis relates this intraday volatility and volume to various aspects of a takeover announcement that proxy for the certainty of payoff to shareholders. Post-announcement volatility is highest when takeover announcements involve share exchange bids which are contested.
Trading volume is highest when bids are contested and involve a large initial price change. This study tests the tax-induced trading hypothesis as an explanation of the turn-of-the-year anomaly using Canadian and U. Since the Canadian tax year-end precedes the calendar year-end by five business days, tax effects may be isolated. We find the anomaly is related to the degree of seller- and buyer-initiated trading and depends upon the incidence of the taxation year-end.
Seller-initiated transactions at bid prices dominate until the tax year-end after which buyer-initiated trades at ask prices dominate. The anomaly is a function of bid-ask prices. This paper develops a variable rate deposit insurance premium model to analyze the impact of stabilization and interim audits. The pricing model incorporates the option of the deposit insurer to stabilize rather than liquidate or merge a distressed financial institution.
Empirical results based on the credit unions of British Columbia indicate that stabilization is least costly given non-trivial liquidation and merger expenses, low audit costs and low volatility of the assets to liabilities ratio. Interim audits are most beneficial for financial institutions which have the lowest audit costs, highest variance of assets to liabilities ratio, lowest liquidation or merger expenses and highest leverage.
A pooled cross-section time series model examined shareholder reaction to the bailout of Canadian Commercial Bank and subsequent runs on deposits at it and other banks. The price of the shares of the non-failed Schedule A chartered banks fell upon announcement of the Canadian Commercial Bank bailout, while the systematic risk of banks with significant oil exposure rose.
Furthermore, news of runs on deposits only affected the common stock of Canada's lower rated banks reflecting the "flight to quality" reaction of depositors. The major deposit insurance system in Canada, like those in other countries, has suffered from the inability of capital markets and regulators to deal appropriately with the system created incentives for insured institutions to take excessive risks. Market and regulatory discipline will strengthen only when the implicit guarantee of depositors in large financial institutions is accounted for and more accurate and complete information about the financial condition of member institutions is revealed to capital markets and regulators.
Consequently, solutions to the problems of deposit insurance system depend on how effectively procedures to enhance disclosure are implemented. A study was conducted of the monthly rates of return available in the Canadian capital market during the years compared with characteristics of returns available to a Canadian investor in the US for the same period. The return series include equities, Treasury bills, federal bonds, and industrial bonds in both Canada and the US and Canadian municipal and provincial bonds.
US return series were adjusted for monthly changes in the value of the Canadian dollar. The return series characteristics studied include: The statistical characteristics of the Canadian and US return series are very similar. However, the variance of monthly equity returns was higher in Canada in the s than previously this was not true of the US data. US monthly returns are not a good leading indicator of Canadian returns.
This paper investigates the production technology facing computerized credit unions in Canada. Dayhoff, who formulated a Markov model of evolution and derived the PAM score matrices. Her estimation procedure for amino acid exchange frequencies is restricted to pairs of proteins that have a constant and small degree of divergence.
Here we present an improved estimator, called the resolvent method, that is not subject to these limitations. This extension of Dayhoff's approach enables us to estimate an amino acid substitution model from alignments of varying degree of divergence.
Extensive simulations show the capability of the new estimator to recover accurately the exchange frequencies among amino acids.
A model of evolutionary change in protein. Atlas of Protein Sequences and Structures, 5, The rapid generation of mutation data matrices from protein sequences. Amino acid substitution during functionally constrained divergent evolution of protein sequences.
I will describe some of these tasks, with the ambition to illustrate the pleasant diversity of subjects. Kim Laurio Manual and semi-manual construction of libraries of patterns, such as PROSITE, is a tedious process involving careful analysis of protein function and manual selection of suitable motifs to be modelled by patterns.
In this talk, we show how this process can be fully automated, and yet result in patterns with higher classification accuracy than those in the PROSITE library. The automated system relies on building accurate multiple alignments, as well as on suitable heuristics for selection of alignment columns from which to build the pattern.
R.W. Robert White | Faculty
These heuristics involve the use of mixtures of Dirichlet distributions to estimate the true distribution corresponding to the alignment column, followed by the calculation of entropy of each estimated distribution as a guide for selection of the most "informative" columns.
Thanks to the fast progress in sequencing world-wide, the number of members has inreased considerably over the last years. The SDR family also contains members with dehydratase, epimerase and isomerase activity. Complexity is also large, with several enzyme activity types, subgroups and evolutionary patterns. Repeated duplications can be traced for the alcohol dehydrogenases, with independent enzymogenesis of ethanol activity, showing a general importance of this enzyme activity.
Protein sequence databases are increasing in size at a rapid pace and offer a valuable source of information. In studies of biological variation, protein family characterisation and evolutionary relationships, these databases are of the outermost importance. However, as the databases expand, the time it takes to perform searches and extract the desired information increases as well. A slightly modified version of the naive algorithm is used for the matching process, where the sequences are matched in an all versus all manner.
The database consists of around entries, half of them originates from the protein databases and the other half from the translation of open reading frames ORFs. KIND will be updated every weeks, and is available via anonymous ftp from ftp: Global Oligonucleotide statistics in random DNA models. Results, open problems, and applications to computational molecular biology. Eric Rivals, LIRMM, Montpellier, France We developed exact and approximate techniques to determine the statistical distribution of the number of missing oligonucleotides of a given length in DNA sequences under various random models of different complexity.
Even in the simplest model, the exact computations can become quite demanding. We propose an efficient method based on the enumeration of all string autocorrelations of length q, i. For this, we present an efficient algorithm. Furthermore, by assuming the words are independent, we obtain very simple approximation formulas, which are shown to be surprisingly good when compared to the exact values. From this, we derive an interesting and so far unproven conjecture. Similar techniques are used to compute the distribution of the number of common oligonucleotides of two sequences.
This knowledge allows to analyze fast database search algorithms which use a technique called "q-gram filtration". This means that in a first fast step, one discards regions of the database that do not share sufficiently many subsequences of length q with the query.
Then, a thorough but slower search for good approximate matches can focus on the remaining fraction of the database. Using our results, we can understand how the performance of QUASAR depends on its parameters, and hence propose optimal parameter sets for various applications. Time permitting, we mention some more applications of oligonucleotide statistics. These include monkey tests for random number generators, which help to ensure that artificially generated test data for any algorithm is not biased by fault of the random number generator.
We also look at the probability of a gene's unique identifiability by any short oligonucleotide within a genome. David Sankoff and Raffaele Giancarlo. Proceedings of the 11th Symposium on Combinatorial Pattern Matching. Sorin Istrail, et al. Here, a sequence is modelled as a stationary ergodic Markov chain.Are we ready to get married?
Special emphasis will be on the joint occurrences of multiple motifs. Here, limit results are obtained, as well as bounds on the distance to the limiting distribution. A complication lies in disentangling the complicated dependence structure between word occurrences, due to self-overlap as well as due to overlap between words. Waterman, Probabilistic and statistical properties of words, to appear in J.
Schbath, Compound Poisson and Poisson process approximation for occurrences of multiple words in Markov chains. The probabilistic distribution of this statistics is necessary to assess the significancy of the observed results. For local analysis, asymptotic results are not relevant since they assume that the observed sequence is infinite. We present here some results on the exact distribution of the occurrences of one or several words in a random sequence generated by a first order Markov process.
This results are obtained through probability generating functions.
Professor Winston Hide - SITraN
The effective calculation of this distributions sometimes induces very long computational times. Three applications are presented: Reproduction is assumed to undergo three stages: Treating individuals as pairs of genes at a certain locus we introduce the diploid ancestral process the past genealogical tree for n such genes sampled in the current generation.
Neither mutation nor selection are assumed. A convergence criterium for the diploid ancestral process is proved as N goes to infinity while n remains unchanged. We specify conditions when the limit process coalescent is the so-called Kingman coalescent and discuss situations when the coalescent allows for multiple mergers of ancestral lines.
Sagitov, The general coalescent with asynchronous mergers of ancestral lines. Sagitov, A classification of coalescent processes for haploid exchangeable population models.